Due to their simple application, skin creams are commonly used to treat medical conditions (e.g., eczema, acne, skin cancer) and to improve skin appearance (e.g., wrinkles, blemishes, hair loss). However, many therapies are not absorbed well by the skin, thereby limiting their effectiveness.
To solve this problem, we developed STAR particles that can be directly incorporated into skin creams. As they are applied, STAR particles make microscopic pores in the skin’s surface that are temporary, invisible and painless; people have described STAR particle application as a mild tingling sensation similar to exfoliating scrubs. Although small, the microscopic pores created by STAR particles dramatically increase skin permeability so that many more types of molecules can be absorbed rapidly and effectively. Additionally, STAR particles can be manufactured at low cost using materials that are safe for the body and the environment. STAR particles are a novel technology that improve delivery and open the door to many skin therapies that have not been possible before.